A Scoping Review : Research Trend pharmacology Of Annona muricata

Abstract

Annona muricata, or soursop, has gained lots of attention in the pharmaceutical field due to its broad therapeutic potential. This research aims to analyze the pharmacological effects of soursop, such as its anticancer, antioxidant, and antidiabetic activities. The method used was a systematic literature review involving article searches using Google Scholar as the database, yielding 2,180 articles published between 2013 and 2024. The study results indicate that 96% ethanol is the most commonly used solvent (17.07%), with human cancer cells as the primary test subjects (21.57%) and soursop leaves as the most frequently used sample part (77%). Maceration is the most commonly applied extraction method (48%), with the most prominent pharmacological effect being anticancer activity (40%). The conclusion of this research highlights the significant potential of
soursop for developing herbal medicines.